Re-representation of liver fat reduces the chances of diabetes without changing the diet

Health and Medical

A recent study revealed that changing the metabolism of fat in the liver can help prevent diabetes, without any changes in the diet.

Initial experiments at the Max Planck Institute for Metabolic Research revealed a number of mice on how to change the metabolism of fat in the liver, reducing the chances of diabetes, without changing a high-fat diet.

"Our bodies store fat in adipose tissue, but after consuming large amounts of material over a long period of time, they begin to multiply in more important places such as the liver, which in turn can lead to diseases," said Dr. Philip Harshmidt, a professor at Washington University School of Medicine. Fatty liver, which can reduce the body's response to insulin and eventually lead to type II diabetes"He said.

"A group of fats known as ceramides have always been associated with these metabolic diseases, and many research in the past has focused on lowering their levels by blocking the proteins they create"He said.

"Other research groups have already shown that blocking ceramide production in rats inhibits the development of insulin resistance, however, this is associated with a large number of side effects"He said.

The researchers tried to get more details. Since the ceramide was created by many different combinations, the team investigated the factors that contribute to insulin resistance. In rats, the team found that the ceramide molecules accumulated in the liver tend to be of a certain length , Indicating that they are generated by ceramides cinnamides 5 and 6, and nothing changed when Ceramide Sinesis 5 was blocked, but when the same happened with Ceramid Senses 6, mice remained less thin, had less fatty liver, improved Glucose metabolism.

(tagsToTranslate) liver (t) diabetes (t) diabetes treatment (t) sugar